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NURS-6630N,Approaches to Treatment.2020 Winter Qtr Midterm Exam - Week 6

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Chemistry

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Question 1 What is the strongest established risk factor for bipolar disorder? Family History  Response Feedback: “The strongest established risk factor for BPD is a family history of BPD.” Question 2 Which of the following medications are known as selective serotonin re-uptake inhibitors (SSRIs)? i. ii. iii. iv. v. Nortriptyline Citalopram Duloxetine Fluoxetine Venlafaxine  Question 3 Which disease state of a non-adherent patient is at greater risk for substance use, violence, and victimization as well as worse overall quality of life? Schizophrenia  Response “Moreover, non-adherent patients with schizophrenia are at greater Feedback: risk for substance use, violence, and victimization as well as worse overall quality of life.” Question 4 Patient is a 72-year-old male with a past medical history significant for atrial fibrillation and COPD with a new diagnosis of major depression disorder. Based on his comorbid conditions, what antidepressant would you recommend as first-line?  ResponseFeedback:(Options C & D are both TCA antidepressants and, based on the patient’s age and comorbid conditions, a TCA would likely result in more side effects, such as increased fall risk due to potential for orthostatic hypotension and anticholinergic-related side effects. In addition, patient has a history for cardiac abnormalities due to A. fib diagnosis - TCAs result in electrocardiographic changes in susceptible individuals, therefore, would likely avoid. Choice B is used more for ADHD purposes than as an antidepressant) Page numbers used: Page 39 for TCA side-effect profile Question 5 Which of the following is an appropriate strategy for managing treatment-resistant depression? Use both SSRI and SNRI  Question 6 Which of the following medications is best to AVOID in maintenance treatment of bipolar disorder and why?  Response “As noted previously, antidepressants may contribute to an Feedback: increase in mood episode frequency.” Question 7 With second-generation antipsychotics, what is the main side effect that requires frequent monitoring?  Response table 7-6 & page 80, table 7-7; Page 78: “However, attention over the Feedback: past decade has focused on effect of second-generation antipsychotics on glucose metabolism and lipids and associated metabolic syndrome.” Question 8 Which amino acid is involved in the synthesis of both norepinephrine and dopamine?  Question 9 An 81-year-old male comes to your clinic today complaining of dry mouth, blurred vision, and constipation. He has a past medical history significant for hypertension, heart failure, and depression. Of the following medications, which one is likely contributing to these side effects?  Response Only TCA is listed with most anticholinergic effects; Page 39 for TCA Feedback: side effect profile: “dry mouth, blurred vision, constipation, urinary hesitancy, tachycardia, memory difficulties, and ejaculatory difficulties” Question 10 Which medication has been studied and recommended in patients with a social anxiety
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